Sunday, January 16, 2011

Age related changes to kidneys

The aging kidney is characterized by:

  1. Loss of renal mass
  2. Arterial sclerosis
  3. Arteriolar hyalinosis
  4. An increased number of sclerotic glomeruli
  5. Loss of tubules
  6. Interstitial fibrosis.

Genetics, hemodynamic factors, diabetes and hypertension all affect changes in the kidney function

Reference:

J Nephrol. The aging kidney: structural changes.Pannarale G, Carbone R, Del Mastro G, Gallo C, Gattullo V, Natalicchio L, Navarra A, Tedesco A.

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