Hypercapnia Strategy To Improve Lung Function

Permissive hypercapnia helps in developing a protective lung ventilatory strategy. Hypercapnic acidosis has shown to be lifesaving in cases of ALI and systemic organ injury. However, more studies need to be done to determine how it affects cases of sepsis and it’s advantage when low tidal volume ventilation for adults with ARDS is considered as a treatment option.

Reference:

Bench-to-bedside review: Permissive hypercapnia, Donall O' Croinin, Martina Ni Chonghaile, Brendan Higgins, and John G Laffey Crit Care.