A new study published in the Diabetes journal found that TRPM2-deficiency (a Ca2+-permeable channel in pancreatic beta-cells ) led to higher blood glucose levels because the ion channel is responsible for modulating insulin secretion.
Reference:
K. Uchida, K. Dezaki, B. Damdindorj, H. Inada, T. Shiuchi, Y. Mori, T. Yada, Y. Minokoshi, M. Tominaga. Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice. Diabetes, 2010
No comments:
Post a Comment