Monday, January 10, 2011

Mechanism and causes of a pleural effusion

  • Altered permeability of membranes: inflammatory process, neoplasm
  • Reduction in intravascular oncotic pressure: hypoalbuminemia, cirrhosis
  • Increased capillary hydrostatic pressure: CHF
  • Inability of lung to expand: atelectasis, mesothelioma
  • Decreased lymphatic drainage: thoracic duct obstruction
  • Increased fluid in peritoneal cavity: migration of fluid across diaphragm via lymphatics
  • Iatrogenic: central line misplacement

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