Thursday, December 30, 2010

Chronic granulomatous disease review

How can a person determine their risk for developing chronic granulomatous disease (CGD is a disease which causes bacteria from Staphylococcus aureus, Aspergillus, abscesses in the lungs, liver, spleen, granulomas causing urinary tract or bladder obstruction)?

Answer: The amount of super oxide produced is correlated with severity of CGD.

Antibiotics and interferon-gamma is the treatment for CGD.

Douglas B. Kuhns, W. Gregory Alvord, Theo Heller, Jordan J. Feld, Kristen M. Pike, Beatriz E. Marciano, Gulbu Uzel, Suk See DeRavin, Debra A. Long Priel, Benjamin P. Soule, Kol A. Zarember, Harry L. Malech, Steven M. Holland, John I. Gallin. Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease. New England Journal of Medicine

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