Saturday, December 25, 2010

Rosacea – Cathelicidin and Corneum Tryptic Enzymes

The peptide cathelicidin within the skin is processed differently in rosacea patients than in individuals not affected by rosacea and induces inflammation that may contribute to rosacea. Rosacea patients have elevated levels of enzymes called stratum corneum tryptic enzymes (SCTE).Patients have the following features:

• Redness on the cheeks, nose, chin or forehead
• Small visible blood vessels on the face
• Bumps or pimples on the face
• Watery or irritated eyes

Factors increasing the risk for rosacea are sun exposure, emotional stress, hot or cold weather, wind, heavy exercise, alcohol, spicy foods, heated beverages, humidity, certain skin-care products and many others.

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