A particular tight junction protein, claudin-1 is reduced in atopic dermatitis (a condition that causes dry, red, itchy skin). New research has found that the stratum corneum and cell-to-cell connections known as tight junctions in skin are faulty for people suffering from atopic dermatitis. Minimize allergens such as pollen, mold, pet dander, dust mites reduces the effect of atopic dermatitis.
Source:
http://www.urmc.rochester.edu/news/story/index.cfm?id=3076
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