A pH below 5 is a sign of healthy skin and healed wounds. A new technology allows doctors to know if a wound is healing or infected by changing color based on the pH. So if there is a shift from the acid to the alkaline, this is a sign that there are complications in the healing of the wound. A pH value between 6.5 und 8.5 means an infection is present.
Reference:
ScienceDaily. from http://www.sciencedaily.com /releases/2010/11/101116093821.htm
A particular tight junction protein, claudin-1 is reduced in atopic dermatitis (a condition that causes dry, red, itchy skin). New research has found that the stratum corneum and cell-to-cell connections known as tight junctions in skin are faulty for people suffering from atopic dermatitis. Minimize allergens such as pollen, mold, pet dander, dust mites reduces the effect of atopic dermatitis.
Source:
http://www.urmc.rochester.edu/news/story/index.cfm?id=3076
Preventing venous stasis ulcers, pressure sores and diabetic foot ulcers is achieved by bioactive peptides promote wound healing. The formation of new blood vessels (angiogenesis) and remodeling of extracellular matrices by collageneses from Clostridium histolyticum bacteria allows for wound healing.
Reference:
Demidova-Rice TN, Geevarghese A, Herman IM. Wound Repair and Regeneration. "Bioactive peptides derived from vascular endothelial cell extracellular matrices promote microvascular morphogenesis and wound healing in vitro.
The peptide cathelicidin within the skin is processed differently in rosacea patients than in individuals not affected by rosacea and induces inflammation that may contribute to rosacea. Rosacea patients have elevated levels of enzymes called stratum corneum tryptic enzymes (SCTE).Patients have the following features:
• Redness on the cheeks, nose, chin or forehead
• Small visible blood vessels on the face
• Bumps or pimples on the face
• Watery or irritated eyes
Factors increasing the risk for rosacea are sun exposure, emotional stress, hot or cold weather, wind, heavy exercise, alcohol, spicy foods, heated beverages, humidity, certain skin-care products and many others.
